Dr. Ganugula is an Assistant Professor in College of Community Health Sciences (CCHS). He is intrigued by the link between carbohydrates-sugar-body (CSB) and how they function with and without insulin. He is motivated to tap the untapped potential of ‘functional foods’, to better understand the CSB link by taking a radical approach and address the general skepticism of the formers practice. He serves as a CO-PI on NIH R01.
Representative Publications
- Ex vivo rat eye model for investigating transport of next generation precision-polyester nanosystems. R. Ganugula, M. Arora, M.N.V. Ravi Kumar. A.C.S. Appl. Mater. Interfaces 9, 25668-25671, 2017.
- Nano-curcumin safely prevents streptozotocin-induced inflammation and apoptosis in pancreatic β-cells for effective management of type 1 diabetes mellitus. R. Ganugula, M. Arora, P. Jaisamut, R. Wiwattanapatapee, H. G. Jorgensen, V. P. Venkatpurwar, B. Zhou, A. R. Hoffmann, S. Guo, M. N. V. Ravi Kumar. Br. J. Pharmacol. 174, 2074-2084, 2017.
- Efficacy of biodegradable curcumin nanoparticles in delaying cataract in diabetic rat model. C.N. Grama, P. Suryanarayana, M. A. Patil, R. Ganugula, M.N.V. Ravi Kumar, G. B. Reddy. PLoS One 8, e78217, 2013.
- Attenuation of diabetic retinopathy in rats by ellagic acid through Inhibition of AGE formation. R. Ganugula, C. Akileshwari, V. S. Reddy, G. B. Reddy. J Food Sci Technol. 54, 2411-2421, 2017.
- Ellagic acid inhibits non-enzymatic glycation and prevents proteinuria in diabetic rats. R. Ganugula, S. Jakhotia, P. Y. Reddy, P. A. Kumar, G. B. Reddy. Food Funct. 7, 1574-1583, 2016.
Research Interests
Over the years, he has generated a significant body of work establishing mechanisms of actions of various functional foods in preventing diabetic eye diseases by targeting multiple pathways of disease progression, and more recently exploring unique attributes of nanotechnology to improvise therapeutic outcomes. In addition, he has expertise in wide range of in vitro, ex vivo and in vivo models, including canine.
